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Golgi staining of aged astrocytes did not show major morphological changes 529 , whereas age-dependent changes in astrocytes stained with antibodies against S100B and glutamine synthetase are characterised by complex region-dependent changes ranging from atrophy to hypertrophy

doi: 10.3390/antiox13060624, 10

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Similar conformational changes between two particle states are seen in other GSH-binding enteroviruses, and thus the use of GSH affinity columns for enterovirus purification will likely select for the D-antigenic states and could lead to loss/removal of material for less stable viruses and VLPs 37